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Metals in Biological Systems PDF Download

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Metals in Biological Systems

Metals in Biological Systems PDF Author: Maureen J. Kendrick
Publisher: Ellis Horwood Limited
ISBN:
Category : Alkali metals
Languages : en
Pages : 192

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Book Description
An examination of the ocurrence of 14 transitional and alkali metals in biological systems, including the structural and physical techniques used to detect and characterize these metal sites. There is also a section focusing on the interaction of inorganic drugs with biomolecules, such as DNA.

Metals in Biological Systems

Metals in Biological Systems PDF Author: Maureen J. Kendrick
Publisher: Ellis Horwood Limited
ISBN:
Category : Alkali metals
Languages : en
Pages : 192

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Book Description
An examination of the ocurrence of 14 transitional and alkali metals in biological systems, including the structural and physical techniques used to detect and characterize these metal sites. There is also a section focusing on the interaction of inorganic drugs with biomolecules, such as DNA.

Bioinorganic Chemistry

Bioinorganic Chemistry PDF Author: Alfred X. Trautwein
Publisher: Wiley-VCH
ISBN:
Category : Science
Languages : en
Pages : 767

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Book Description
Whenever nature has a difficult task to perform it can be expected that a metal ion or a cluster of such ions is employed. Metal ions are indispensable for the integrity of biological structures and the catalysis of biological reactions. Knowledge about their mode of action, their uptake in the cell, their handling and their storage is important for the development of new pharmaceuticals. This book summarizes latest results of interdisciplinary research on several universities.

Metals in Biology

Metals in Biology PDF Author: Lawrence Berliner Graeme Hanson
Publisher:
ISBN: 9781441911407
Category :
Languages : en
Pages : 440

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Book Description
Metal ions in biology is an ever expanding area in science and medicine involving metal ions in proteins and enzymes, their biosynthesis, catalysis, electron transfer, metal ion trafficking, gene regulation and disease. While X-ray crystallography has provided snapshots of the geometric structures of the active site redox cofactors in these proteins, the application of high resolution EPR spectroscopy in conjunction with quantum chemistry calculations has enabled, in many cases, a detailed understanding of a metalloenzymes mechanism through investigations of the geometric and electronic struct.

Cellular and Molecular Biology of Metals

Cellular and Molecular Biology of Metals PDF Author: Rudolfs K. Zalups
Publisher: CRC Press
ISBN: 9781420059984
Category : Science
Languages : en
Pages : 440

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Book Description
With chapter contributions from more than 30 metal biology experts, Cellular and Molecular Biology of Metals explains the role of key divalent metal ions involved in the molecular and cellular biology of various target cell populations. Although it primarily focuses on homeostatic metals, such as nickel, zinc, and chromium, the text also discusses a few environmentally pertinent, toxic divalent cations, including mercury, cadmium, and arsenic. This authoritative resource reviews the physiological mechanisms underlying the handling of essential and toxic metal ions, including metal ion homeostasis, metals and enzyme activity, metals and transcriptional regulation, and metal ion transport. It also analyzes other functions designed to avoid metal-induced toxicity and mediate the metal enhancement of cellular function. The role of metal ions and their effect on mammalian cells and organs are only beginning to be truly defined. Cellular and Molecular Biology of Metals arms metals toxicologists and cellular and molecular biologists with the necessary knowledge they need to take the research effort to the next level.

Metals in Biology

Metals in Biology PDF Author: Graeme Hanson
Publisher: Springer
ISBN: 1441911391
Category : Medical
Languages : en
Pages : 419

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Book Description
Metal ions in biology is an ever expanding area in science and medicine involving metal ions in proteins and enzymes, their biosynthesis, catalysis, electron transfer, metal ion trafficking, gene regulation and disease. While X-ray crystallography has provided snapshots of the geometric structures of the active site redox cofactors in these proteins, the application of high resolution EPR spectroscopy in conjunction with quantum chemistry calculations has enabled, in many cases, a detailed understanding of a metalloenzymes mechanism through investigations of the geometric and electronic structure of the resting, enzyme-substrate intermediates and product complexes. This volume, Part II of a two-volume set demonstrates the application of high resolution EPR spectroscopy in determining the geometric and electronic structure of active site metal ion centers in iron sulfur cluster containing metalloproteins, mononuclear molybdenum metalloenzymes, manganese-containing enzymes and novel metalloproteins.

Metals Ions in Biological System

Metals Ions in Biological System PDF Author: Astrid Sigel
Publisher: CRC Press
ISBN: 020390933X
Category : Science
Languages : en
Pages : 856

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Book Description
Volume 39: Molybdenum and Tungsten: Their Roles in Biological Processes is devoted soley to the vital research area on molybdenum and tungsten and their role in biology. It offers a comprehensive and timely account of this fascinating topic by 40 distinguished international authorities. Topics include: transport, homeostasis, regulation and binding

Metals in Cells

Metals in Cells PDF Author: Valeria Culotta
Publisher: John Wiley & Sons
ISBN: 1118636864
Category : Science
Languages : en
Pages : 608

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Book Description
Over the last three decades a lot of research on the role of metals in biochemistry and medicine has been done. As a result many structures of biomolecules with metals have been characterized and medicinal chemistry studied the effects of metal containing drugs. This new book (from the EIBC Book Series) covers recent advances made by top researchers in the field of metals in cells [the “metallome”] and include: regulated metal ion uptake and trafficking, sensing of metals within cells and across tissues, and identification of the vast cellular factors designed to orchestrate assembly of metal cofactor sites while minimizing toxic side reactions of metals. In addition, it features aspects of metals in disease, including the role of metals in neuro-degeneration, liver disease, and inflammation, as a way to highlight the detrimental effects of mishandling of metal trafficking and response to "foreign" metals. With the breadth of our recently acquired understanding of metals in cells, a book that features key aspects of cellular handling of inorganic elements is both timely and important. At this point in our understanding, it is worthwhile to step back and take an expansive view of how far our understanding has come, while also highlighting how much we still do not know. The content from this book will publish online, as part of EIBC in December 2013, find out more about the Encyclopedia of Inorganic and Bioinorganic Chemistry, the essential online resource for researchers and students working in all areas of inorganic and bioinorganic chemistry.

Metal Ions in Biological Systems

Metal Ions in Biological Systems PDF Author: Helmut Sigel
Publisher: CRC Press
ISBN: 9780367454210
Category :
Languages : en
Pages : 352

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Book Description
Metal Ions in Biological Systems is devoted to increasing our understanding of the relationship between the chemistry of metals and life processes. The volumes reflect the interdisciplinary nature of bioinorganic chemistry and coordinate the efforts of researchers in the fields of biochemistry, inorganic chemistry, coordination chemistry, environmental chemistry, biophysics, pharmacy, and medicine. Volume 44 offers 9 timely and authoritative chapters focused on vital research areas concerning the biogeochemistry of metals. Supported by nearly 60 illustrations and tables, topics include the atmospheric transport of metals, studies the marine biogeochemistry of iron, and its impact on the carbon cycle; the bioavailability of trace metals in freshwater environments and in soils; the uptake of heavy metals by higher plants, algae, and cyanobacteria; the microbial transformations of radionuclides; and the biogeochemistry of carbonates.

Bioinorganic chemistry : metals in biology

Bioinorganic chemistry : metals in biology PDF Author: Mordechai Chevion
Publisher:
ISBN:
Category : Biochemistry
Languages : en
Pages : 90

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Book Description


Transition Metals in Biochemistry

Transition Metals in Biochemistry PDF Author: A. S. Brill
Publisher: Springer Science & Business Media
ISBN: 3642811485
Category : Science
Languages : en
Pages : 186

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Book Description
Transition metal ions in biological systems are of interest in biology, biochemistry, chemistry, medicine, and physics. Scien tists with rather different viewpoints, employing many methods, have contributed to this area. A concise review of the current state of the field will, to some extent, reflect the special knowledge of the person writing it - in this case application of physical methods to the investigation of metal coordination. x ray diffraction is one of the most important of these methods, but a useful treatment of X-ray structure analysis would be com parable in size with and beyond the scope of the monograph. Many results of X-ray diffraction studies are, of course, presented. Electron paramagnetic resonance spectroscopy has played a major part in the rapid advance in knowledge of the electronic struc tures of transition metal ions in biological systems. More gener ally, measurements involving light, microwaves, and magnetic fields are capable of producing much new information, and the required instrumentation is available at most research institu tions. Therefore light absorption and paramagnetic resonance are treated in depth. The principles described in the latter discus sions are broadly applicable, for example to the promising tech niques of X-ray spectroscopy (utilizing synchrotron radiation) and lanthanide-perturbed, very high-resolution nuclear magnetic resonance spectroscopy.